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师资力量

  • 姓  名:罗俊杰
  • 性  别:男
  • 职  称:副教授
  • 所在系别:营养与健康系
  • 办公地点:中国农业大学建大校区1号楼
  • 电子邮箱:luojj@pku.edu.cn
个人简历

2020.06-至今:中国农业大学,优秀人才引进,副教授

2016.07-2020.06:北京食品营养与人类健康创新中心,岗位科学家

2013.07-2016.06:北京大学,博士后

2008.09-2013.06:中国农业大学,理学博士

2004.09-2008.06:中国农业大学,工学学士


研究方向

1.  食物健康效应与疾病干预

2.  线粒体与心血管疾病、癌症以及代谢综合征

3.  线粒体DNA突变与基因编辑

课题项目

1.   国家重点研发计划: 低 GI烘焙类全麦面制主食食品创制关键技术,2024-2027,子课题负责人

2.  国家重点研发计划:特医食品核心原料、关键工艺及产品稳定性研究,2022-2026,子课题负责人

3.  横向项目:某药抗缺氧作用能量代谢机制测试,2022-2023,主持

4.  国家自然科学基金面上项目:哺乳动物中miRNA抑制作用的分子机制及调控网络的演化规律,2016-2019,参与

5.  国家自然科学基金重大研究计划:果蝇转座元件和piRNA之间的基因组冲突及对杂交不育的影响,2015-2017 ,参与

论文著作

1.  Luo Y#, Luo J#, An P#, Zhao Y#, Zhao W#, Fang Z, Xia Y, Zhu, L, Xu T, Zhang X, et al. The activator protein-1 complex governs a vascular degenerative transcriptional programme in smooth muscle cells to trigger aortic dissection and rupture. European heart journal 2024, 45, 287-305, doi:10.1093/eurheartj/ehad534.

2.  Xu T#, Zhang X#, Zhao W, Shi J, Wan S, Zhang Y, Hao Y, Sun M, He J, Jiang L, Wang H, Gao H*, Luo J*, Luo Y*, An P*. Foxo1 is an iron-responsive transcriptional factor regulating systemic iron homeostasis. Blood 2024, 144, 1314-1328, doi:10.1182/blood.2024024293.

3.  Zhao W#, Chen J#, Xia Y#, Wei Z, Wan S, Guo H, Hao Y, Jiang W, Zhang H, Ren F*, An P*, Luo Y*, Luo J*. Temporal-specific single-cell atlas of human type A aortic dissection reveals immune cell dynamics and therapeutic targets. Science Bulletin 2024, 10.1016/j.scib.2024.07.001, doi:10.1016/j.scib.2024.07.001.

4.  Wang X#, Ji Y#, Qi J, Zhou S, Wan S, Fan C, Gu Z, An P*, Luo Y*, Luo J*. Mitochondrial carrier 1 (MTCH1) governs ferroptosis by triggering the FoxO1-GPX4 axis-mediated retrograde signaling in cervical cancer cells. Cell death & disease 2023, 14. doi:10.1038/s41419-023-06033-2.

5.  Zhu L#, Li D#, Zhang X, Wan S, Liu Y, Zhang H, Luo J*, Luo Y*, An P*, Jiang W*. Comparative efficacy on outcomes of C-CABG, OPCAB and ONBEAT in coronary heart disease: A systematic review and network meta-analysis of randomized controlled trials. International Journal of Surgery 2023, 10.1097/js9.0000000000000715. doi:10.1097/js9.0000000000000715.

6.  Yu S#, Luo J#, Song Z, Ding F, Dai Y, Li N*. Highly efficient modification of beta-lactoglobulin (BLG) gene via zinc-finger nucleases in cattle. Cell research 2011, 21(11):1638-40. doi: 10.1038/cr.2011.153.

7.  Luo S#, He F#, Luo J#, Dou S#, Wang Y, Guo A, Lu J*. Drosophila tsRNAs preferentially suppress general translation machinery via antisense pairing and participate in cellular starvation response. Nucleic acids research 2018, 46(10):5250-68. doi: 10.1093/nar/gky189.

8.  Zhang X, Zhang Z, Wan S, Qi J, Hao Y, An P, Luo Y*, Luo J*. Ameliorative Effect of Coenzyme Q10 on Phenotypic Transformation in Human Smooth Muscle Cells with FBN1 Knockdown. International journal of molecular sciences 2024, 25, 2662, doi:10.3390/ijms25052662.

9. Wang Z, Zhou S, Hao Y, Xu T, An P*, Luo Y*, Luo J*. Nicotinamide mononucleotide protects against high-fat-diet-induced atherosclerosis in mice and dampens aortic inflammation and oxidative stress. Journal of Functional Foods 2024, 112, 105985, doi:10.1016/j.jff.2023.105985.

10. Zhou S#, Cheng F#, He J, Xu T, Zhang X, Wan S, Qi J, He J, Chen F, Luo J*, Luo Y*, An P*. Effects of high-quality protein supplementation on cardiovascular risk factors in individuals with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials. Clinical Nutrition 2024, 43, 1740-1750, doi:10.1016/j.clnu.2024.06.013.

11.  Xia Y#, Zhang X#, An P, Luo J*, Luo Y*. Mitochondrial Homeostasis in VSMCs as a Central Hub in Vascular Remodeling. International journal of molecular sciences 2023, 24. doi:10.3390/ijms24043483.

12.  Luo J*, Luo Y*. The Effects of Dietary Protein and Polysaccharide Fortification on Disease. Nutrients 2023, 15, 4137. doi:10.3390/nu15194137.

13.  Wang Z#, Jin D#, Zhou S, Dong N, Ji Y, An P, Wang J*, Luo Y*, Luo J*. Regulatory roles of copper metabolism and cuproptosis in human cancers. Frontiers in oncology 2023, 13, 1123420. doi:10.3389/fonc.2023.1123420.

14.  Qi J#, An P#, Jin D, Ji Y, Wan S, Zhang X, Luo Y*, Luo J*, Zhang C*. Food groups and urologic cancers risk: a systematic review and meta-analysis of prospective studies. Frontiers in Nutrition 2023, 10. doi:10.3389/fnut.2023.1154996.

15.  Zhou S#, Wang Z, Hao Y, An P, Luo J*, Luo Y*. Dandelion Polysaccharides Ameliorate High-Fat-Diet-Induced Atherosclerosis in Mice through Antioxidant and Anti-Inflammatory Capabilities. Nutrients 2023, 15, 4120. doi:10.3390/nu15194120.

16.  Ji Y#, Jin D#, Qi J, Wang X, Zhang C, An P, Luo Y*, Luo J*. Fucoidan Protects against Doxorubicin-Induced Cardiotoxicity by Reducing Oxidative Stress and Preventing Mitochondrial Function Injury. International journal of molecular sciences 2022, 23. doi:10.3390/ijms231810685.

17.  Wang X#, Ji Y, Jin D, Qi J, Hou X, Zhao W, Zhou S, Zhang C*, Luo Y*, An P*, Luo J*. Natural Polysaccharide beta-Glucan Protects against Doxorubicin-Induced Cardiotoxicity by Suppressing Oxidative Stress. Nutrients 2022, 14. doi:10.3390/nu14040906.

18.  Zhang L#, Qi J, Zhang X, Zhao X, An P*, Luo Y*, Luo J*. The Regulatory Roles of Mitochondrial Calcium and the Mitochondrial Calcium Uniporter in Tumor Cells. International journal of molecular sciences 2022, 23. doi:10.3390/ijms23126667.

19.  Wang Y#, Wang X#, Long Q#, *, Liu Y, Yin T, Sirota I, Ren F, Gu Z*, Luo J*. Reducing embryonic mtDNA copy number alters epigenetic profile of key hepatic lipolytic genes and causes abnormal lipid accumulation in adult mice. The FEBS journal 2021. doi: 10.1111/febs.16121.

20.  Xu T#, Zhang X, Liu Y, Wang H, Luo J*, Luo Y*, An P*. Effects of dietary polyphenol supplementation on iron status and erythropoiesis: a systematic review and meta-analysis of randomized controlled trials. The American journal of clinical nutrition 2021. doi: 10.1093/ajcn/nqab068.

21.  An P#, Xu W#, Luo J* and Luo Y*. Expanding TOR complex 2 signaling: Emerging regulators and new connections. Frontiers in Cell and Developmental Biology 2021. doi: 10.3389/fcell.2021.713806.

22.  Wu J#, Lin D#, Jiu L, Liu Q, Gu Z, Luo J*, Zhao Y*. Exploring epigenetic biomarkers of universal specificities and commonalities among pan-cancer cohorts in The Cancer Genome Atlas. Epigenomics 2021, 13(8):599-612. doi: 10.2217/epi-2021-0050.

23.  Wang X#, An P#, Gu Z, Luo Y*, Luo J*. Mitochondrial Metal Ion Transport in Cell Metabolism and Disease. International journal of molecular sciences 2021, 22(14). doi: 10.3390/ijms22147525.

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