2020.05-至今:中国农业大学,优秀人才引进,副教授
2016.05-2020.04:北京食品营养与人类健康高精尖创新中心,岗位科学家
2014.12-2016.04:中国科学院生物物理研究所,副研究员
2012.07-2014.11:中国科学院生物物理研究所,助理研究员
2007.09-2012.06:中国科院生物物理研究所,细胞生物学,理学博士
2003.09-2007.06:四川大学,生命科学学院,生物科学,学士
血管生物学与心血管疾病
1. 国家重点研发计划子课题,2024-2028,在研,主持
2. 国家重点研发计划子课题,2022-2026,在研,主持
3. 国家自然科学基金面上项目,2022-2025,在研,主持
4. 国家自然科学基金面上项目,2020-2023,结题,主持
5. 国家自然科学基金青年基金,2014-2016,结题,主持
6. 北京市自然科学基金面上项目,2022-2024,在研,主持
7. 中国农业大学科创项目,2021-2021,结题,主持
8. 中央高校基本科研业务费专项资金项目,2020-2020,结题,主持
9. 横向项目,2021-2022,在研,主持
1. Junjie Luo#, Yongting Luo#. The Effects of Dietary Protein and Polysaccharide Fortification on Disease. Nutrients. ISSN (Print):1871-5230 (论著)
2. Yongting Luo*, Junjie Luo*, Peng An*, Yuanfei Zhao*, Wenting Zhao*, Zhou Fang, Yi Xia, Lin Zhu, Teng Xu, Xu Zhang, Shuaishuai Zhou, Mingyan Yang, Jiayao Li, Junming Zhu, Yongmin Liu, Haiyang Li, Ming Gong, Yuyong Liu, Jie Han, Huiyuan Guo#, Hongjia Zhang#, Wenjian Jiang#, Fazheng Ren#. The AP-1 complex governs a vascular degenerative transcriptional program in smooth muscle cells to trigger aortic dissection and rupture. Eur Heart J. 2023 Nov 22:ehad534.
—Editorial Comment: Miteva K. On target inhibition of vascular smooth muscle cell phenotypic transition underpins TNF-OXPHOS-AP-1 as a promising avenue for anti-remodelling interventions in aortic dissection and rupture. Eur Heart J. 2023 Nov 24:ehad679
3. Luo Y*, Duan H*, Qian Y*, Feng L, Wu Z, Wang F, Feng J, Yang D, Qin Z, Yan X#. Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis. Cell Research. 2017;27(3):352-372. (封面文章)
4. Yongting Luo#, Xiao Teng, Lingling Zhang, Jianan Chen, Zheng Liu, Xuehui Chen, Shuai Zhao, Sai Yang, Jing Feng, Xiyun Yan#. CD146-HIF-1α hypoxic reprogramming drives vascular remodeling and pulmonary arterial hypertension. Nature Communications. 2019 Aug 7;10(1):3551.
5. Jianan Chen*, Yongting Luo*, Hui Hui, Tanxi Cai, Hongxin Huang, Fuquan Yang, Jing Feng, Jingjing Zhang#, Xiyun Yan#. CD146 coordinates brain endothelial cell-pericyte communication for blood-brain barrier development. Proc Natl Acad Sci U S A. 2017;114(36):E7622-E7631. (Faculty 1000 Prime推荐)
6. Wenyi Xu, Huijuan Hua, Yueh-Ho Chiu, Guannan Li, Huihan Zhi, Zhengquan Yu, Fazheng Ren, Yongting Luo#, Wei Cui#. CD146 regulates growth factor-induced mTORC2 activity independent of PI3K and mTORC1 pathways. Cell Reports. 2019 Oct 29;29(5):1311-1322
7. Jianan Chen*, Yongting Luo*, Hongxin Huang, Shuilong Wu, Jing Feng, Jingjing Zhang, Xiyun Yan#. CD146 is essential for PDGFRβ-induced pericyte recruitment. Protein & Cell, 2018;9(8):743-747.
8. Lingling Zhang*, Yongting Luo*, Xiao Teng, Zhenzhen Wu, Mengtao Li, Dong Xu, Qian Wang, Fei Wang, Jing Feng#, Xiaofeng Zeng#, Xiyun Yan#. CD146: a potential therapeutic target for systemic sclerosis. Protein & Cell, 2018 ;9(12):1050-1054.
9. Xuan Wang*, Yuting Ji*, Jingyi Qi, Shuaishuai Zhou, Sitong Wan, Chang Fan, Peng An#, Yongting Luo#, Junjie Luo#. Mitochondrial carrier 1 (MTCH1) governs ferroptosis by triggering the FoxO1-GPX4 axis-mediated retrograde signaling in cervical cancer cells. Cell Death & Disease. 2023 Aug 8;14(8):508.
10. Xu T, Zhang X, Liu Y, Wang H, Luo J#, Luo Y#, An P#. Effects of dietary polyphenol supplementation on iron status and erythropoiesis: a systematic review and meta-analysis of randomized controlled trials. Am J Clin Nutr. 2021 Apr 19:nqab068
11. Lin Zhu*, Dongjie Li*, Xu Zhang, Sitong Wan, Yuyong Liu, HongJia Zhang, Junjie Luo#, Yongting Luo#, Peng An#, Wenjian Jiang#. Comparative efficacy on outcomes of C-CABG, OPCAB and ONBEAT in coronary heart disease: A systematic review and network meta-analysis of randomized controlled trials. Int J Surg. 2023 Sep 18. doi: 10.1097/JS9.0000000000000715.
12. Luo Y*, Zheng C*, Zhang J, Lu D, Zhuang J, Xing S, Feng J, Yang D, Yan X#. Recognition of CD146 as an ERM-binding protein offers novel mechanisms for melanoma cell migration. Oncogene. 2012;31(3):306-21.
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