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师资力量

  • 姓  名:孙佳增
  • 性  别:男
  • 职  称:副教授
  • 所在系别:营养与健康系
  • 办公地点:中国农业大学建大校区1号楼
  • 电子邮箱:sunjiazeng331@163.com
个人简历

2022.07-至今:中国农业大学,优秀人才引进,副教授

2018.04-2022.03:美国普渡大学,博士后

2014.08-2021.03:中国医学科学院基础医学研究所,助理研究员

2009.09-2014.07:中国农业大学,理学博士

2005.09-2009.07:河北科技师范学院,理学学士

研究方向

衰老与抗病毒免疫

过敏性疾病发病机制与防治

疫苗与抗体开发

益生菌和酵母工程化改造及应用

课题项目

1. “十四五”国家重点研发计划(2024-2027)子课题,主持

2. 河南省重大科技专项(2024-2026)子课题,主持

3. 河南省自然基金面上项目(2024-2025),主持

4. 国家乳业技术创新中心项目子课题(2024-2027),主持

5. 国家乳业技术创新中心项目子课题(2024-2026),主持

6. 营养与健康系科研创新能力提升专项(2023),主持

7. 教育部重点实验室科研能力提升项目(2024),主持

8. 北京自然科学基金青年项目(2016-2017),主持

9. 北京协和医学院“协和青年科研基金”(2017-2018),主持

10. 北京生命科技研究院重大项目(2024-2026),项目骨干

11. 国家自然科学基金面上项目(2017-2020),合作单位负责人

论文著作

1. Sun J, Wu G, Pastor F, Rahman N, Wang WH, Zhang Z, Merle P, Hui L, Salvetti A, Durantel D, Yang D, Andrisani O*. RNA helicase DDX5 enables STAT1 mRNA translation and interferon signaling in hepatitis B virus replicating hepatocytes. Gut. 71(5):991-1005,2022.

2. Rahman N#, Sun J#, Li Z#, Pattnaik A, Mohallem R, Wang M, Kazemian M, Aryal U, Andrisani O*. The cytoplasmic LSm1-7 and nuclear LSm2-8 complexes exert opposite effects on Hepatitis B virus biosynthesis and interferon response. Front. Immunol. 13:970130,2022.

3. Wei Y, Peng J, Wang S, Ding Z, Chen G, Sun J*. Probiotics and the Potential of Genetic Modification as a Possible Treatment for Food Allergy. Nutrients. 2023.15:(4159).

4. Ding Z, Wei Y, Peng J, Wang S, Chen G, Sun J*. The Potential Role of C-Reactive Protein in Metabolic-Dysfunction-Associated Fatty Liver Disease and Aging. Biomedicines. 2023. 11:(2711).

5. Sun J#, Zhang S#, Shi B, Zheng D, Shi J*. Transcriptome identified lncRNAs associated with renal fibrosis in UUO rat model. Front. Physiol. 8:658,2017.

6. Sun J, Wang J, Wang S, Yuan D, Li Z, Yi B, Hou Q, Mao Y, Liu W*. MicroRNA miR-320a and miR-140 inhibit mink enteritis virus infection by repression of its receptor, feline transferrin receptor. Virol. J. 11(1):210,2014.

7. Sun J, Wang J, Wang S, Yuan D, Birame BM, Li Z, Yi B, Liu W*. MicroRNA profile analysis of a feline kidney cell line before and after infection with mink enteritis virus. Gene. 539: 224-229,2014.

8. Sun J, Wang J, Yuan D, Wang S, Li Z, Yi B, Mao Y, Hou Q, Liu W*. Cellular microRNA miR-181b inhibits replication of mink enteritis virus by repression of non-structural protein 1 translation. PLoS One. 8 (12): e81515,2013.

9. Li Z, Caron de Fromentel C, Kim W, Wang WH, Sun J, Yan B, Utturkar S, Lanman NA, Elzey BD, Yeo Y, Zhang H, Kazemian M, Levrero M, Andrisani O*. LevreroRNA helicase DDX5 modulates sorafenib sensitivity in hepatocellular carcinoma via the Wnt/β-catenin-ferroptosis axis. Cell Death Dis. 14(11):786,2023.

10. Wu J, Zhang M, Zhang H, Sheng M, Sun J, Wu F, Gao H, Chen L, Li Z, Tian Q, Zhu L, Fang B*. PMN-MDSC: A Culprit Behind Immunosenescence and Increased Susceptibility to Clostridioides difficile Infection During Aging. Engineering. 42:59-73.

11. Xiong W, Fang B, Wang X, Zhang M, Du M, Sun J, Chen J, Li Y, Sun C, Lei X, Zhang X, Ren F*. Dietary Lipid Intervention in the Prevention of Brain Aging. Engineering. 37:128-137.

12. Jie Ma, Yingying Lin, Wei Xiong, Xiaoxue Liu, Minghui Pan, Jiazeng Sun, Yanan Sun, Yixuan Li, Huiyuan Guo, Guofang Pang, Xiaoyu Wang *, Fazheng Ren*. The microRNA-29ab1/Zfp36/AR axis in the hypothalamus regulates male-typical behaviors in mice. IJMS. 2024.

13. Li C, Lu Y, Wang J, Liu B, Szeto I, Zhang W, Bi R, Duan S, Quan R, Wang X, Li Y, Xiong W, Sun J, Sun Y*.Immunoregulation of bovine lactoferrin together with osteopontin promotes immune system development and maturation. Food Funct. 15(2):866-880,2024.

14. Ma S, Sun J, Guo Y, Zhang P, Liu Y, Zheng D, Shi J*. Combination of AAV-TRAIL with miR-221-Zip therapeutic strategy overcomes the resistance to TRAIL induced apoptosis in liver cancer. Theranostics. 7(13):3228-3242,2017.

15. Han T, Jing X, Bao J, Zhao L, Zhang A, Miao R, Guo H, Zhou B, Zhang S, Sun J, Shi J*. H. pylori infection alters repair of DNA double-strand breaks via SNHG17. J. Clin. Invest. 130(7):3901-3918,2020.

16. Mani SKK, Yan B, Cui Z, Sun J, Utturkar S, Foca A, Fares N, Duantel D, Lanman N, Merle P, Kazemian M, Andrisani O*. Restoration of RNA helicase DDX5 suppresses hepatitis B virus (HBV) biosynthesis and Wnt signaling in HBV-related hepatocellular carcinoma. Theranostics. 10(24):10957-10972,2020.

17. Zhao L, Han T, Li Y, Sun J, Zhang S, Liu Y, Shan B, Zheng D, Shi J*. The lncRNA SNHG5/miR-32 axis regulates gastric cancer cell proliferation and migration by targeting KLF4. FASEB J. 31(3):893-903,2017.

18. Li Z, Wang J, Yuan D, Wang S, Sun J, Yi B, Hou Q, Mao Y, Liu W*. A recombinant canine distemper virus expressing a modified rabies virus glycoprotein induces immune responses in mice. Virus Genes. 50(3):434-441,2015.

19. Yuan D, Wang J, Li Z, Mao Y, Sun J, Xi J, Wang S, Hou Q, Yi B, Liu W*. Establishment of a rescue system for an autonomous Parvovirus mink enteritis virus. Virus Res. 183:1-5,2014.

20. Wang S, Zhang P, He F, Wang JG, Sun J, Li ZL, Yi B, Xi J, Mao YP, Hou Q, Yuan DL, Zhang ZD, Liu WQ. Combination of specific single chain antibody variable fragment and siRNA has a synergistic inhibitory effect on the propagation of avian influenza virus H5N1 in chicken cells. Virol. J. 11:208,2014.

21. Yi B, Wang J, Wang S, Yuan D, Sun J, Li Z, Mao Y, Hou Q, Liu W. Overexpression of Banna mini-pig inbred line fatty acid binding protein 3 promotes adipogenesis in 3T3-L1 preadipocytes. Cell Biol. Int. 38(8):918-923,2014.

22. Birame BM, Wang J, Yu F, Sun J, Li Z, Liu W*. Potentiation of apoptin-induced apoptosis by cecropin B-Like antibacterial peptide ABPs1 in human HeLa cervical cancer cell lines is associated with membrane pore formation and caspase-3 activation. J. Microbiol. Biotechnol. 24(6):756–764,2014.

23. Birame BM, Wang J, Yu F, Wang S, Yuan D, Sun J, Li Z, Yi B, Liu W*. Co-expression of apoptin (VP3) and antibacterial peptide cecropin B mutant (ABPS1) genes induce higher rate of apoptosis in HepG2 and A375 cell lines. Afr. J. Biotechnol. 11(49):10981-10988,2012.


获得奖项

1. 2023中国商业联合会科技进步特等奖 (12/13).  

2. 2024中国制品工业会二等3/14.

3. 2023第九届北京市大学生生物学竞赛三等奖指导教师.

4. 2024营养与健康系第二届青年教师教学基本功比赛二等奖.


出版著作

1. 《食品产业高质量发展战略研究》,科学出版社,编委.

2. 《生命早期1000天营养改善与应用前沿》,化学工业出版社,编委.

3. 云享数字化教材生化综合实验技术》,云教材,编委.

4. 中国农业大学教学研究项目,编委.


社会兼职

1. 北京慢性病防治与健康教育研究会感染性疾病专业委员会青年常务委员.

2. 第三届《食品研究与开发》青年编委会委员.

3. Nutrients客座编辑.

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